منابع مشابه
FDG PET in Dementia
Positron emission tomography (PET) is a branch of Nuclear Medicine, a new novel way of functional imaging using radioisotopes, which has a significant role in all aspects of dementia-early diagnosis, differential diagnosis, and the assessment of drug treatment. [18F] Fluorodeoxyglucose (FDG) allows measurement of cerebral glucose metabolism both qualitatively and quantitatively. The metabolic a...
متن کاملComparison of 18F-FDG and PiB PET in cognitive impairment.
UNLABELLED The purpose of this study was to compare the diagnostic accuracy of glucose metabolism and amyloid deposition as demonstrated by (18)F-FDG and Pittsburg Compound B (PiB) PET to evaluate subjects with cognitive impairment. METHODS Subjects were selected from existing participants in the Mayo Alzheimer's Disease Research Center or Alzheimer's Disease Patient Registry programs. A tota...
متن کاملFDG PET imaging in patients with pathologically verified dementia.
UNLABELLED The purpose of this study was to confirm with pathologic verification 2 beliefs related to Alzheimer's disease (AD): (a) the long-standing impression that bilateral temporo-parietal hypometabolism, as noted on FDG PET imaging, is the metabolic abnormality associated with Alzheimer's disease (AD) and (b) that the sensitivity, specificity, and diagnostic accuracy of the metabolic patte...
متن کاملAutopsy as gold standard in FDG-PET studies in dementia.
Positron emission tomography (PET) imaging with F18-fluorodeoxyglucose (FDG) is increasingly used as an adjunct to clinical evaluation in the diagnosis of dementia. Considering that most FDG-PET studies in dementia use clinical diagnosis as gold standard and that clinical diagnosis is approximately 80% sensitive or accurate, we aim to review the evidence-based data on the diagnostic accuracy of...
متن کاملGender differences in healthy aging and Alzheimer's Dementia: A 18 F-FDG-PET study of brain and cognitive reserve.
Cognitive reserve (CR) and brain reserve (BR) are protective factors against age-associated cognitive decline and neurodegenerative disorders. Very limited evidence exists about gender effects on brain aging and on the effect of CR on brain modulation in healthy aging and Alzheimer's Dementia (AD). We investigated gender differences in brain metabolic activity and resting-state network connecti...
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ژورنال
عنوان ژورنال: Clinical and Translational Imaging
سال: 2013
ISSN: 2281-5872,2281-7565
DOI: 10.1007/s40336-013-0029-8